Substitution Editing in tRNAs Web Site

Editing of Acanthamoeba castellani mitochondrial tRNAs - arrows indicate nt changes
(from Lonergan and Gray, 1993)

Purpose:

• This site is intended to act as a source of information on the substitution RNA editing that occurs in tRNAs in Acanthomoeba mitochondria, Marsupial mitochondria, etc, and to increase the interactions between researchers in this field. A list of all researchers and their email addresses and any available postdoctoral positions, literature references, sequence databases specific for this field, and upcoming scientific meetings will be presented. In addition, there will be a section with data taken from published and unpublished research to illustrate research problems and research directions.

List of selected references:

1. Lonergan, K. M., and Gray, M. W. Editing of Transfer RNAs in Acanthamoeba castellanii Mitochondria. Science 259: 812-816 (1993) (MED)
2. Morl, M., Dorner, M., Paabo, S. C to U editing and modifications during the maturation of the mitochondrial tRNA^Asp in marsupials. Nucl. Acids Res. 23: 3380-3384 (1995) (MED)
3. Yokobori, S. Paabo, S. Transfer RNA editing in land snail mitochondria. Proc. Natl. Acad. Sci. 92: 10432-10435 (1995) (MED)
4. Borner, G. V., Morl, M., Janke, A., Paabo, S. RNA editing changes the identity of a mitochondrial tRNA in marsupials. EMBO J. 15: 5949-5957 (1996) (MED)
5. Price, D.H. and Gray, M.W. A novel nucleotide incorporation activity implicated in the editing of mitochondrial transfer RNAs in Acanthamoeba castellani. RNA 5: 302-17 (1999) (MED) (Note: This paper is not included in the course reader).
6. Price, D.H.and Gray, M.W. Confirmation of predicted edits and demonstration of unpredicted edits in Acanthamoeba castellani mitochondrial tRNAs. Cur. Genet. 35: 23-29 (1999). (MED)

To return to the main RNA Editing site, click here.

Site created and maintained by L. Simpson. Last updated on 2-4-2003.