Gene: Cytochrome oxidase 2 
Species: Trypanosoma brucei
Notes: The 5' ends of edited and preedited mRNAs were mapped by 
primer extension to +1 (A. Estevez and L. Simpson, unpublished).



       1 ---------+---------+---------+---------+---------+---------+ 60
DNA      ATCTAAATGTAATAATAACAAATGAGTTTTATATTAACTTTTTGAATGATATTTTTAATG
RNA-ed   AUCUAAAUGUAAUAAUAACAAAUGAGUUUUAUAUUAACUUUUUGAAUGAUAUUUUUAAUG
       1 ---------+---------+---------+---------+---------+---------+ 60
AA                            M  S  F  I  L  T  F  W  M  I  F  L  M   
                            1 -  -  -  -  -  -  -  -  -  +  -  -  -   13


      61 ---------+---------+---------+---------+---------+---------+ 120
         GATTCAATAATTGTATTAATATCTTTTTCAATATTTCTATCTGTATGAATATGTGCATTG
         GAUUCAAUAAUUGUAUUAAUAUCUUUUUCAAUAUUUCUAUCUGUAUGAAUAUGUGCAUUG
      61 ---------+---------+---------+---------+---------+---------+ 120
         D  S  I  I  V  L  I  S  F  S  I  F  L  S  V  W  I  C  A  L   
      14 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -   34


     121 ---------+---------+---------+---------+---------+---------+ 180
         ATTATAGCAACAGTATTAACTGTAACAAAAATAAATAATATATATTGTACATGAGATTTT 
         AUUAUAGCAACAGUAUUAACUGUAACAAAAAUAAAUAAUAUAUAUUGUACAUGAGAUUUU
     121 ---------+---------+---------+---------+---------+---------+ 180
         I  I  A  T  V  L  T  V  T  K  I  N  N  I  Y  C  T  W  D  F   
      35 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -    54


     181 ---------+---------+---------+---------+---------+---------+ 240
         ATATCATCAAAATTTATAGATACATATTGGTTTGTACTTGGAATGATGTTTATATTGTGT
         AUAUCAUCAAAAUUUAUAGAUACAUAUUGGUUUGUACUUGGAAUGAUGUUUAUAUUGUGU
     181 ---------+---------+---------+---------+---------+---------+ 240
         I  S  S  K  F  I  D  T  Y  W  F  V  L  G  M  M  F  I  L  C   
      55 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -    74


     241 ---------+---------+---------+---------+---------+---------+ 300
         TTATTGTTAAGGTTGTGTTTGTTGTTGTATTTTAGTTGTATAAATTTTGTGAGTTTTGAT
         UUAUUGUUAAGGUUGUGUUUGUUGUUGUAUUUUAGUUGUAUAAAUUUUGUGAGUUUUGAU
     241 ---------+---------+---------+---------+---------+---------+ 300
         L  L  L  R  L  C  L  L  L  Y  F  S  C  I  N  F  V  S  F  D   
     75  -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -    94


     301 ---------+---------+---------+---------+---------+---------+ 360
         TTGTGTAAAGTAATAGGTTTTCAGTGATATTGGGTATATTTTTTATTTGGAGAAACCACG
         UUGUGUAAAGUAAUAGGUUUUCAGUGAUAUUGGGUAUAUUUUUUAUUUGGAGAAACCACG
     301 ---------+---------+---------+---------+---------+---------+ 360
         L  C  K  V  I  G  F  Q  W  Y  W  V  Y  F  L  F  G  E  T  T   
     95  -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -   114


     361 ---------+---------+---------+---------+---------+---------+ 420
         ATATTTAGTAATTTAATATTAGAAAGTGATTATTTAATAGGAGATTTAAGAATATTACAG
         AUAUUUAGUAAUUUAAUAUUAGAAAGUGAUUAUUUAAUAGGAGAUUUAAGAAUAUUACAG
     361 ---------+---------+---------+---------+---------+---------+ 420
         I  F  S  N  L  I  L  E  S  D  Y  L  I  G  D  L  R  I  L  Q   
     115 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -   134


     421 ---------+---------+---------+---------+---------+---------+ 480
         TGTAACCATGTATTGACATTGTTAAGTTTGGTTATTTATAAATTATGAGTATCTGCAGTA
         UGUAACCAUGUAUUGACAUUGUUAAGUUUGGUUAUUUAUAAAUUAUGAGUAUCUGCAGUA
     421 ---------+---------+---------+---------+---------+---------+ 480
         C  N  H  V  L  T  L  L  S  L  V  I  Y  K  L  W  V  S  A  V   
     135 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -   154


     481 ---------+---------+---------+---------+-------  - - +------ 536
         GATGTAATACACTCATTTACAATATCAAGTTTAGGTATAAAAGTAGA  G A ACCTGGT
         GAUGUAAUACACUCAUUUACAAUAUCAAGUUUAGGUAUAAAAGUAGAuuGuAuACCUGGU
     481 ---------+---------+---------+---------+---------+---------+ 540
         D  V  I  H  S  F  T  I  S  S  L  G  I  K  V  D  C  I  P  G   
     155 -  -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -   174


     537 ---+---------+---------+---------+---------+---------+------ 596
         AGGTGTAATGAAATAATTTTGTTTGCTACAAATAACGCAACTCTTTACGGACAATGTAGT
         AGGUGUAAUGAAAUAAUUUUGUUUGCUACAAAUAACGCAACUCUUUACGGACAAUGUAGU
     541 ---------+---------+---------+---------+---------+---------+ 600
         R  C  N  E  I  I  L  F  A  T  N  N  A  T  L  Y  G  Q  C  S   
     175 -  -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  -  -   195


     597 ---+---------+---------+---------+---------+---------+------ 656
         GAATTGTGTGGTGTATTACACGGTTTTATGCCTATTGTAATAAATTTTATATAGAAAGGT
         GAAUUGUGUGGUGUAUUACACGGUUUUAUGCCUAUUGUAAUAAAUUUUAUAUAGAAAGGU
     601 ---------+---------+---------+---------+---------+---------+ 660
         E  L  C  G  V  L  H  G  F  M  P  I  V  I  N  F  I  * 
     196 -  -  -  +  -  -  -  -  -  -  -  -  -  +  -  -  -  213


     657 ---+---------+---------+---------+- 691
         ATATAATCTATAATGAAAGGGGATTTTAAGATTGG
         AUAUAAUCUAUAAUGAAAGGGGAUUUUAAGAUUGG
     661 ---------+---------+---------+----- 695